Metallothionein as an Anti-Inflammatory Mediator

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Metallothionein as an Anti-Inflammatory Mediator

The integration of knowledge concerning the regulation of MT, a highly conserved, low molecular weight, cystein-rich metalloprotein, on its proposed functions is necessary to clarify how MT affects cellular processes. MT expression is induced/enhanced in various tissues by a number of physiological mediators. The cellular accumulation of MT depends on the availability of cellular zinc derived f...

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Comments to Metallothionein as an Anti-Inflammatory Mediator

Dear Editor, This paper introduces MTs as metalloproteins and their role in various inflammatory diseases. In the conclusion section, the authors state that MT-induction/enhancement and/or zinc supplementation to induce/enhance MT might be possible therapeutic options for inflammatory diseases [1]. To be an appropriate therapy on the level of genetics or molecule, the option should be well medi...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 2009

ISSN: 0962-9351,1466-1861

DOI: 10.1155/2009/101659